The end of 2025 has seen a surge of humanitarian crises and geopolitical tensions across the Middle East and beyond, as conflicts, sanctions, and military threats converge in several regions.
Sudan: el-Fasher a 'Crime Scene' After RSF Takeover
United Nations aid workers visiting Sudan's northern city of el-Fasher for the first time since it fell under the control of the UAE-backed Rapid Support Forces (RSF) described the city as a "crime scene." The RSF captured the city from the Sudanese Armed Forces after more than 500 days of siege. UN officials reported widespread destruction, few remaining residents, and growing concern over those injured or detained. Satellite imagery revealed traces of blood and evidence of mass atrocities, including executions and sexual violence. Over 100,000 people have fled the city since late October.
Palestinian Prisoners Face Systematic Abuse
Meanwhile, Palestinian rights groups accused Israel of committing "systematic genocide" against prisoners in its custody. Reports indicate that at least 32 Palestinians died in detention in 2025, while tens of thousands have been arrested across the West Bank and Jerusalem, including children and women. According to advocacy organizations, detainees face torture, medical neglect, sexual violence, and mass isolation, with authorities withholding information about many prisoners' whereabouts.
Iran Responds to US Threats
Tensions between Washington and Tehran remain high after former US President Donald Trump threatened renewed strikes on Iran's nuclear and missile facilities. Iranian officials warned that any aggression would provoke a "severe and regret-inducing" response. The warning comes just months after a devastating 12-day conflict in June, during which Israel and the US launched hundreds of strikes on Iranian territory, leaving over 1,100 Iranians dead. Iranian leadership insists the country is now better prepared for confrontation, despite international pressure.
US Sanctions Venezuelan Firm Over Iran Drone Deal
In a related development, the US Department of the Treasury announced sanctions against Venezuelan company Empresa Aeronautica Nacional SA and its chairman for allegedly assisting Iran in producing drones. The sanctions freeze US-based assets and bar Americans from engaging in financial transactions with the firm. The move highlights ongoing US concerns over the proliferation of Iranian military technology in Latin America.
Yemen Cancels UAE Defence Deal Amid Rising Tensions
Finally, Yemen's Presidential Leadership Council canceled a defence agreement with the UAE, ordering Emirati forces to leave the country within 24 hours. Abu Dhabi denied accusations of supporting southern separatists while affirming its commitment to Saudi security. The dispute follows months of friction over UAE counterterrorism operations in southern Yemen.
From Sudan to Yemen, and from the West Bank to Iran and Venezuela, 2025 has closed with escalating conflicts, sanctions, and humanitarian crises. Analysts warn that these intertwined issues could further destabilize regional and global security if unresolved.