In or about the year 570 the child who would be named Muhammad and who would become the Prophet of one of the world's great religions, Islam, was born into a family belonging to a clan of Quraysh, the ruling tribe of Mecca, a city in the Hijaz region of northwestern Arabia.

Originally the site of the Ka'bah, a shrine of ancient origins, Mecca had with the decline of southern Arabia become an important center of sixth-century trade with such powers as the Sassanians, Byzantines, and Ethiopians. As a result the city was dominated by powerful merchant families among whom the men of Quraysh were preeminent.

Muhammad's father, 'Abd Allah ibn'Abd al-Muttalib, died before the boy was born; his mother, Aminah, died when he was six. The orphan was consigned to the care of his grandfather, the head of the clan of Hashim. After the death of his grandfather, Muhammad was raised by his uncle, Abu Talib. As was customary, Muhammad as a child was sent to live for a year or two with a Bedouin family. This custom, followed until recently by noble families of Mecca, Medina, Tayif, and other towns of the Hijaz, had important implications for Muhammad. In addition to enduring the hardships of desert life, he acquired a taste for the rich language so loved by the Arabs, whose speech was their proudest art, and learned the patience and forbearance of the herdsmen, whose life of solitude he first shared and then came to understand and appreciate.

About the year 590, Muhammad, then in his twenties, entered the service of a widow named Khadijah as a merchant actively engaged with trading caravans to the north. Sometime later Muhammad married Khadijah, by whom he had two sons - who did not survive - and four daughters.

During this period of his life Muhammad traveled widely. Then, in his forties he began to retire to meditate in a cave on Mount Hira outside of Mecca, where the first of the great events of Islam took place. One day, as he sat in the cave, he heard a voice, later identified as that of the Angel Gabriel, which ordered him to:

Three times Muhammad pleaded his inability to do so, but each time the command was repeated. Finally, Muhammad recited the words of what are now the first five verses of the 96th surah or chapter of the Quran - words which proclaim God the Creator of man and the Source of all knowledge.

At first Muhammad divulged his experience only to his wife and his immediate circle. But as more revelations enjoined him to proclaim the oneness of God universally, his following grew, at first among the poor and the slaves, but later also among the most prominent men of Mecca. The revelations he received at this time and those he did so later are all incorporated in the Quran, the Scripture of Islam.

Not everyone accepted God's message transmitted through Muhammad. Even in his own clan there were those who rejected his teachings, and many merchants actively opposed the message. The opposition, however, merely served to sharpen Muhammad's sense of mission and his understanding of exactly how Islam differed from paganism. The belief in the unity of God was paramount in Islam; from this all else followed. The verses of the Quran stress God's uniqueness, warn those who deny it of impending punishment, and proclaim His unbounded compassion to those who submit to His will. They affirm the Last Judgment, when God, the Judge, will weigh in the balance the faith and works of each man, rewarding the faithful and punishing the transgressor. Because the Quran rejected polytheism and emphasized man's moral responsibility, in powerful images, it presented a grave challenge to the worldly Meccans.